bioprotocols.info
free online protocols for biomedical research
PubMed  I  Cell    Nature   Science   Scientific American  I  HHMI    Nobelprize  I  Weather    
Home > Reagent And Buffer Recipes

20X SSPE Buffer Recipe

Component Amount Stock 20X concentration Final 1X concentration
NaCl 175.3g 3 M 150 mM
NaH2PO4xH2O 27.6g 200 mM 10 mM
Na2EDTA 7.4g 200 mM 10 mM

Dissolve the reagents in 800 ml ultrapure water.
Adjust pH to 7.4 with 10 M NaOH.
Bring volume to 1 liter with ultrapure water.
Sterilize by autoclaving.

Good luck with your DNA and RNA hybridization experiments!