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Category: peptide

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DnaSP v5: a software for comprehensive analysis of DNA polymorphism data

Posted on June 27, 2021April 29, 2021 by Oscar

DnaSP v5: a software for comprehensive analysis of DNA polymorphism data DnaSP is a software package for a comprehensive analysis of DNA polymorphism data. Version 5 implements a number of new features and analytical methods allowing extensive DNA polymorphism analyses on large datasets. Among other features, the newly implemented methods allow for: (i) analyses on multiple data files; (ii) haplotype phasing;… Continue reading

bioprotocols

DNA sequencing with chain-terminating inhibitors

Posted on June 27, 2021April 29, 2021 by Oscar

DNA sequencing with chain-terminating inhibitors A new method for determining nucleotide sequences in DNA is described. It is similar to the “plus and minus” method [Sanger, F. & Coulson, A. R. (1975) J. Mol. Biol. 94, 441-448] but makes use of the 2′,3′-dideoxy and arabinonucleoside analogues of the normal deoxynucleoside triphosphates, which act as specific chain-terminating inhibitors… Continue reading

bioprotocols

Chromatin modifications and their function

Posted on April 27, 2021April 27, 2021 by Oscar

Chromatin modifications and their function The surface of nucleosomes is studded with a multiplicity of modifications. At least eight different classes have been characterized to date and many different sites have been identified for each class. Operationally, modifications function either by disrupting chromatin contacts or by affecting the recruitment of nonhistone proteins to chromatin. Their… Continue reading

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